Glutathione Peroxidase (GPx) Small molecule selenium based glutathione peroxidase 4 mimetic inhibits lipid peroxidation and protects cultured neurons from ferroptosis ScienceDirect What is the role of selenium in supporting glutathione peroxidase activity? Selenium is one of the few nutrients that directly controls how your body handles oxygen at the cellular level. Every time your cells produce energy, they generate peroxides as a byproduct. That Ebselen, Glutathione peroxidase mimic (TBI2288) Tribioscience Keshan Disease, Selenium Deficiency, and the Selenoproteome New England Journal of Medicine